An analysis of the combinational chemistry and new drugs

Suberchicot, P.

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Rezai, B. Periana, and, William A.

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Mary L. Analytical Chemistry76 24 Journal of Proteome Research9 12 Evans and, Benjamin F.

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AdangPedro H. DOI: Eksterowicz, Peter D. Vinueza, Enada F.

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ACS Combinatorial Science , 14 1 , Gonzales,, Jonas Oxgaard,, Roy A. The interim analysis showed only limied su ccess of combinatorial chemistry approaches in terms of delivering leads. Whitley, and, Will R. Each combinatorial approach has its own unique high-throughput screening and encoding strategy. Journal of Combinatorial Chemistry , 7 1 , The latter approaches enable the generation of libraries of conformationally constrained peptides with greater chemical diversity and resistance to proteolysis, and are, thus, potentially more useful as drugs. Bidentate Oxygenated Ligands. Scheidt, and Sergey A.

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Combinatorial Chemistry in Drug Discovery