Human haemoglobin and sickle cell disease biology essay

Sickle cell anemia genetics

People should check with their doctors for more information about using these tactics to avoid infections. It causes pain, organ damage, and anemia low blood count. If you have the disorder, you inherited one gene for hemoglobin S from each of your parents. Women who are pregnant should receive extra care and attention to find and treat problems before they arise. Because of this, smoking may be seen as one of the biggest avoidable risk factors for people with SCD. It comes from substitutions between a single amino acid and a component protein of hemoglobin. The first reported case of sickle cell anemia however was in , when an autopsy of a runaway slave showed an absence of a spleen. The purpose of this essay is to analyze the research on how human genes can evolve to better survive their environment. Sickle Cell disease is inherited and it affects the anatomy of the red blood cells, resulting in a sickle shape which then affects the functions of red blood cells causing a blood disorder. Gill, V. Some people have severe symptoms and others could just be mild. The porphyrin ring is wedged into its pocket by a phenylalanine of its polypeptide chain. Parents of children with SCD should stop smoking as well, in order to protect their children.

The Sickle Cell gene needs to be inhered from both of the parents; otherwise the individual will only carry the Sickle Cell trait. Hemoglobin has played a spectacular role in the history of biology, chemistry, and medicine.

The haemoglobin atom has combine parts: an alpha and a beta.

Sickle cell thesis statement

Over the years the prognosis for these individuals has drastically improved. The disease is deadly when left untreated. Patients with reference to sickle cell suffering take on a variation in a gene on chromosome 11 that codes for the beta subunit of the haemoglobin protein. If the sickle cell trait is carried by an individual they can be asymptomatic. Research shows that among those affected the most with the sickle cell gene are African Americans. Some of the variants have been associated with clinical conditions. Furthermore, the construction of an atomic model of the hemoglobin molecule based on a high-resolution x-ray analysis by Dr. The CDC also recommend that antibiotics be taken every day until the age of 5. People should check with their doctors for more information about using these tactics to avoid infections. For this endeavor he was awarded the Nobel Prize in chemistry in

One of the most recognized populations of vulnerable people are children; furthermore, by adding an inherited disease process, that decreases the immune system, would only increase the vulnerability of the population. This causes the red blood cell to become gelatinous when deoxygenated 2.

Human haemoglobin and sickle cell disease biology essay

This is due to a the high occurrence of malaria in these regions, however, the rate at which both sickle cell anemia and malaria are occurring in other regions of the globe is becoming increasingly prevalent. The CDC also advise adults to get the flu vaccine every year, as well as the pneumococcal vaccine and any others recommended by a person's doctor. Sickle Cell is a recessive disease and persons affected have both copies of the hemoglobin S gene. In , Dr. However, there are specific groups of people who are likely more prone to this disease than any other group. These are all used to track a patient's risk for complications from SCD. Corresponding author. If you have the disorder, you inherited one gene for hemoglobin S from each of your parents. Parents of children with SCD should stop smoking as well, in order to protect their children. Treating symptoms is handled differently in every situation. More than 70, Americans have sickle cell anemia. The first reported case of sickle cell anemia however was in , when an autopsy of a runaway slave showed an absence of a spleen. Sickle cell anemia is a disease in which the body is unable to produce normal hemoglobin, an iron-containing protein. Attention Getter: A sickle is a blade used by farmers to cut down grains and crops. Hemoglobin has played a spectacular role in the history of biology, chemistry, and medicine.

Some of the variants have been associated with clinical conditions. With this research paper, I plan to answer these questions that I have been having for so many years.

Sickle cell disease uk essay

There are often combinations of pain medication and relief techniques used to treat symptoms like acute and chronic pain. Furthermore, the accumulation of the sickle cell gene in malarial regions of the world became a convincing illustration of evolution by natural selection 3. People should work directly with their doctor to determine the best plan of action. Sickle Cell disease is inherited and it affects the anatomy of the red blood cells, resulting in a sickle shape which then affects the functions of red blood cells causing a blood disorder. Women who are pregnant should receive extra care and attention to find and treat problems before they arise. Her main complaints were cough, vague pains in legs joints , night sweats, abdominal pain, less hunger, and increasing weakness. Hemoglobin Hb it is an oxygen transporting molecule, carrying oxygen from the lungs to the tissues and takinge carbon dioxide away from the cell. Because of this, it is important to think of the long-term options that will enable a person with SCD to lead a long and happy life. Some infants though, do not show any signs until the age of four months. Some people may also need blood transfusions, particularly if they have had a stroke from SCD. Sickle Cell is a recessive disease and persons affected have both copies of the hemoglobin S gene. Sickle cell anemia is a blood disease that is inherited. In a person with SCD, this is especially dangerous because their blood is already prone to having low oxygen levels. To date, well over hemoglobin variants have been described. Sickle red blood cells become hard, sticky and shaped like sickles used to cut wheat.

The first reported case of sickle cell anemia however was inwhen an autopsy of a runaway slave showed an absence of a spleen. Sickle cell is an inherited blood disorder that affects red blood cells due to the presence of an abnormal form of hemoglobin, namely hemoglobin S.

Sickle red blood cells become hard, sticky and shaped like sickles used to cut wheat.

risk factors of sickle cell anemia
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Applications and skills: Sickle cell anemia